Pain

Vaccine Could Protect Against Stroke And Epilepsy Damage February 25, 2000 A new oral vaccine has offered new hope because of its effectiveness in protecting laboratory rats against brain damage from epilepsy and stroke, and might one day be used to help humans with the same conditions. The vaccine blocks a protein in the brain called NMDA, but does so only when epilepsy or stroke occur. The vaccine is released in the brain as needed and is …

…barrier is a protective mechanism that prevents many large molecules, such as these antibodies, from entering the brain. Yet during times of neurological insult, like epilepsy and stroke, the blood brain barrier is compromised, and the antibodies do enter the brain. They then seek out and block the NMDA receptor, preventing some brain damage from occurring. Soon afterwards, the blood brain barrier is restored, and the antibodies no longer have an effect on the brain.