Parathormone Report (What it is, the role in the body, disorders linked to it)

Parathormone (PTH) is a polypeptide of 84 amino acids that is produced and secreted by parathyroid chief cells. PTH regulates the concentration of calcium ions (Ca2+) in the blood, this is important because Ca2+ is need for proper muscle and nerve function. Low calcium blood levels (hypocalcemia) cause muscle spasms, tetany and cardiac problems. PTH also regulates blood phosphate and magnesium levels. High blood calcium levels (hypercalcemia) with high blood phosphate levels can cause precipitation of …

…stones, and decalcification of bone will occur. This happens because too much calcium is taken from the bones and put into the blood, as the kidneys try to rid your body of excess calcium the calcium and phosphorus accumulates and precipitates causing kidney stones. If there is a deficit of this hormone hypocalcemia (too low blood calcium concentration) occurs because the calcium is being absorbed by the bones, this can cause muscle or nerve malfunction.