Preparation of a vesicle suspension containing methylene blue as a hydrophilic model drug.

Introduction Colloid drug delivery systems (CDDSs) are vesicular dosage forms. They include liposomes niosomes nanospheres and nanocapsules. Their size avoids any risk of embolism following intravenous injection. CDDSs were initially designed, and were studied, as drug carriers for targeting purposes. The assumption was the expected ability of CDDSs to concert the drug at the therapeutic target and/or divert if from the toxicological one. Some interesting results have been obtained with drugs possessing a narrow …

…Loy and Anna M. Fadda Niosomes as carriers for tretinoin: II. Influence of vesicular incorporation on tretinoin photostability, International Journal of Pharmaceutics, Volume 260, Issue 2, 24 July 2003, Pages 261-272 - Yongmei Hao, Fenglin Zhao, Na Li, Yanhong Yang and Ke'an Li Studies on a high encapsulation of colchicine by a niosome system, International Journal of Pharmaceutics, Volume 244, Issues 1-2, 5 September 2002, Pages 73-80 - formulation Dept, Liposomes and Niosomes in drug delivery, Sunderland University, lecture supplement, 2004, pp 1-8