The Genetic Aspects of Infertility

Infertility or the inability to reproduce, affects males and females as well. It is caused by numerous factors such as a trinucleotide repeat expansion in the androgen-receptor gene in males, or a luteinizing hormone deficiency in females (Lee SL, et al, 1996; Dowsing AT, et al., 1999; Nachtigall LB, et al., 1997). In the past, the causes of infertility were unknown. This is due to the fact that symptoms are hardly ever detectable. Most infertile individuals do not …

…factors that can cause infertility in males and females as well. Problems such as hormone deficiencies, and defective receptor genes are known to cause this condition. A greater awareness of the symptoms and of the condition itself may lead to earlier diagnosis and better treatment. Knowledge of the genetic basis is also essential to enable appropriate counseling of patients and to develop, where possible effective treatment plans (Dowsing AT, et al., 1999; Nachtigall LB, et al., 1997).