Explain how homopoiesis occurs and how it results in mature red blood cells.

Explain how homopoiesis occurs and how it results in mature red blood cells. How are other formed elements in blood made? Explain how homopoiesis is regulated by negative feedback mechanism. Describe three conditions, which would interfere with this and result in anemias. The process of homopoiesis takes place in the red bone marrow, which is a soft network of reticular connective tissue that borders on wide blood capillaries called sinusoids. In this network are immature …

…of red blood cells include blood loss and bone marrow failure. Hemorrhagic anemias result from blood loss. In hemolytic anemias, erythrocytes rupture prematurely. Low hemoglobin content occurs when hemoglobin molecules are normal but erythrocytes contain fewer than usual number and a nutritional anemia is suspected. Iron-deficiency anemia results from inadequate intake of iron-containing foods and impaired iron absorption. Abnormal hemoglobin usually has a genetic basis. Sickle cell anemia is caused by abnormal formation of hemoglobin.