genetics

8 May 1997. Webmaster comments on recent publications: 1. Prof. Dr. Rudi Glockshuber has kindly informed me that: The coordinates of the mouse prion fragment PrP(121-231) will be posted online on October 1, 1997. (I'll post a interactive joystick model of this). His group has a paper currently in press with PNAS concerning the species barrier problem, positions of variable residues in the 3D structure, and possible sites of interactions between PrPc and PrPsc .. A second paper on the …

…to form complementary pairs with an earlier repeat, 3' exonuclease action, and extention. Deletions are similar but on the template strand. Wobble pairs aren't polymerase errors, but rather bases that have come to be errors only through slippage to an imperfect repeat. Predictions of the ! model are testable, using newly discovered cases of familial CJD: Familial CJD with a five-repeat octapeptide insert mutation Cochran,E.J...Goldfarb,L.G. and Brown,P. ------------------------------------------------------------------------ **Bibliography** none